Pachymic acid modified carbon nanoparticles reduced angiogenesis via inhibition of MMP-3.

@article{Ma2015PachymicAM,
  title={Pachymic acid modified carbon nanoparticles reduced angiogenesis via inhibition of MMP-3.},
  author={Jun Ma and Jun Liu and Chun-wei Lu and Dingfang Cai},
  journal={International journal of clinical and experimental pathology},
  year={2015},
  volume={8 5},
  pages={5464-70}
}
Angiogenesis is a process of new blood vessel generation, which is consistently and robustly correlated with tumor formation, growth, and metastasis. The disruption of angiogenesis, and the imbalanced endothelial remodeling and regression, are the main pathogenesis of malignant tumor. Recently, multi-walled nanotubes (MWNTs) have been proposed as a new tool for drug delivery in cancer treatment, which also displayed anti-angiogenic property. In the present study, we modified MWNTs with pachymic… CONTINUE READING

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