PYY-mediated fatty acid induced intestinal differentiation

@article{Aponte2002PYYmediatedFA,
  title={PYY-mediated fatty acid induced intestinal differentiation},
  author={Gregory W. Aponte},
  journal={Peptides},
  year={2002},
  volume={23},
  pages={367-376}
}
  • G. Aponte
  • Published 1 February 2002
  • Biology
  • Peptides
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Only minor differences in DI transcriptional gene expression was observed between fish fed the GM and non-GM maize diets, and Expression of a clone showing high protein similarity to proton-dependent high-affinity oligopeptide transporter was significantly upregulated in fish-fed GM maize compared with fish- fed non- GM maize.
Mice lacking FABP9/PERF15 develop sperm head abnormalities but are fertile.
Membrane Organization and Dynamics in Mammalian Sperm
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This paper presents a meta-analyses of the determinants of Membrane properties and dynamics in sperm and their effects on capacitation and apoptosis.

References

SHOWING 1-10 OF 121 REFERENCES
Expression of intestinal fatty acid binding protein in intestinal epithelial cell lines, hBRIE 380 cells.
TLDR
The data show that I-FABP expression is limited to a differentiated population of hBRIE 380i cells and that the expression can be regulated by factors present in the extracellular matrix as well as involved in regulation of replication or metabolic state of the cell.
Regulation of gene expression by dietary fat.
TLDR
The effects of fatty acids on the genome provide new insight into how dietary fat might play a role in health and disease.
Fatty acids in cell signalling: modulation by lipid binding proteins.
Evidence for transcriptional induction of the liver fatty-acid-binding-protein gene by bezafibrate in the small intestine.
TLDR
The results demonstrate that the mouse terminal ileum is a useful system for studying the regulation of L-FABPc gene expression both in vivo and in vitro and indicate that the transcription of the L-fABpc gene is induced by bezafibrate via de novo protein synthesis and components of sunflower oil can transcriptionally activate the L.FABC gene.
Role of fatty acid-binding protein in cardiac fatty acid oxidation
TLDR
Evidence is presented that FABP is a powerful regulator of acylcarnitine flux entering the mitochondrial β-oxidative system and appears to be an active link between the cytoplasm and the mitochondria, regulating the energy made available to the cell.
Fatty Acid Transfer from Liver and Intestinal Fatty Acid-binding Proteins to Membranes Occurs by Different Mechanisms*
TLDR
The results strongly suggest that fatty acid transfer from I-FABP to membranes occurs by direct collisional interaction of the protein with the phospholipid bilayer, which is consistent with an aqueous diffusion-mediated process.
Fatty acid-binding protein in small intestine. Identification, isolation, and evidence for its role in cellular fatty acid transport.
TLDR
The preponderance of FABP in villi from proximal and middle intestine, its ability to bind fatty acids in vivo as well as in vitro, and its response to changes in dietary fat intake support the concept that this protein participates in cellular fatty acid transport during fat absorption.
Research of an in vitro model to study the expression of fatty acid-binding proteins in the small intestine
TLDR
It is demonstrated for the first time that organ culture of intestinal expiants provides a useful model for studying in vitro the simultaneous regulation of I- and L-FABPc expressions and fibrate peroxisome-proliferators exert a direct effect on I-and L-Binding Proteins expression in the small intestine.
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