PVN lesions prevent the endothelin 1-induced increase in arterial pressure and vasopressin.

Abstract

Endothelin (ET) acts within the central nervous system to increase arterial pressure and arginine vasopressin (AVP) secretion. This study assessed the role of the paraventricular nuclei (PVN) in these actions. Intracerebroventricular ET-1 (10 pmol) or the ET(A) antagonist BQ-123 (40 nmol) was administered in conscious intact or sinoaortic-denervated (SAD… (More)

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@article{Rossi2001PVNLP, title={PVN lesions prevent the endothelin 1-induced increase in arterial pressure and vasopressin.}, author={Noreen F. Rossi and Haiying Chen}, journal={American journal of physiology. Endocrinology and metabolism}, year={2001}, volume={280 2}, pages={E349-56} }