PVN-hindbrain pathway involved in the hypothalamic hyperphagia-obesity syndrome.

@article{Kirchgessner1988PVNhindbrainPI,
  title={PVN-hindbrain pathway involved in the hypothalamic hyperphagia-obesity syndrome.},
  author={Annette L Kirchgessner and Anthony Sclafani},
  journal={Physiology & behavior},
  year={1988},
  volume={42 6},
  pages={517-28}
}
This study examined the involvement of caudal brainstem projections of the hypothalamic paraventricular nucleus (PVN) in the medial hypothalamic (MH) hyperphagia-obesity syndrome. Experiment 1 demonstrated that a unilateral parasagittal knife cut in the MH combined with a contralateral coronal knife cut in either the ventrolateral pons (vP) or ventrolateral medulla (vM) significantly increased food intake and body weight in adult female rats. Overeating and overweight were also produced by a… CONTINUE READING