PU.1 exhibits partial functional redundancy with Spi-B, but not with Ets-1 or Elf-1.

@article{GarrettSinha2001PU1EP,
  title={PU.1 exhibits partial functional redundancy with Spi-B, but not with Ets-1 or Elf-1.},
  author={Lee Ann Garrett-Sinha and Richard Dahl and S Rao and Kevin P. Barton and M. Celeste Simon},
  journal={Blood},
  year={2001},
  volume={97 9},
  pages={
          2908-12
        }
}
Previously it was shown that the Ets proteins, PU.1 and Spi-B, exhibit functional redundancy in B lymphocytes. To investigate the possibility that PU.1 or Spi-B or both share overlapping roles with Ets-1 or Elf-1, PU.1(+/-)Ets-1(-/-), PU.1(+/-)Elf-1(-/-), and Spi-B(-/-)Ets-1(-/-) animals were generated. No blood cell defects were observed in these animals except those previously reported for Ets-1(-/-) mice. Therefore, no genetic overlap was detected between PU.1 or Spi-B with Ets-1 or Elf-1… 
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