PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease

@article{Johansson2006PTPN22PA,
  title={PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease},
  author={Martin Johansson and Lisbeth {\"A}rlestig and G{\"o}ran Hallmans and Solbritt Rantap{\"a}{\"a}-Dahlqvist},
  journal={Arthritis Research & Therapy},
  year={2006},
  volume={8},
  pages={R19 - R19}
}
We analysed relationships between the PTPN22 1858 polymorphism and antibodies to cyclic citrullinated peptide (CCP), rheumatoid factors (RFs) and the shared epitope (SE) gene (HLA-DRB1*0404 or 0401) and determined their combined predictive value for rheumatoid arthritis (RA) in individuals who subsequently developed RA. This case-control study was nested within the Medical Biobank of Northern Sweden. Patients with RA (n = 92) were identified from amongst blood donors antedating onset of disease… CONTINUE READING

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Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not with Crohn's disease, in Canadian populations

  • M van Oene, RF Wintle, +7 authors W Greer
  • Arthritis Rheum
  • 2005
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