PTP1B regulates neurite extension mediated by cell-cell and cell-matrix adhesion molecules.

@article{Pathre2001PTP1BRN,
  title={PTP1B regulates neurite extension mediated by cell-cell and cell-matrix adhesion molecules.},
  author={Purnima Pathre and Carlos O. Arregui and Thomas Wampler and I Kue and Thomas King Chor Leung and Jack Lilien and Janne Balsamo},
  journal={Journal of neuroscience research},
  year={2001},
  volume={63 2},
  pages={143-50}
}
N-cadherin and beta1-integrin adhesion and signaling play important roles in growth cone adhesion and guidance. Each of these adhesion receptor systems is composed of multiprotein complexes, and both adhesion and downstream signaling events are regulated through the interaction of protein tyrosine kinases and phosphatases with many of the proteins that make up these complex systems. Work from our laboratory reported that the nonreceptor protein tyrosine phosphatase PTP1B is localized to… CONTINUE READING
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