PTP1B promotes cell proliferation and metastasis through activating src and ERK1/2 in non-small cell lung cancer.

@article{Liu2015PTP1BPC,
  title={PTP1B promotes cell proliferation and metastasis through activating src and ERK1/2 in non-small cell lung cancer.},
  author={Hong-bing Liu and Ying Wu and Suhua Zhu and Wenjun Liang and Zhaofeng Wang and Yunfen Wang and Tang-feng Lv and Yanwen Yao and Dongmei Yuan and Yong Song},
  journal={Cancer letters},
  year={2015},
  volume={359 2},
  pages={218-25}
}
Previous studies have demonstrated that protein tyrosine phosphatase 1B (PTP1B) can promote tumor progression in breast cancer, colon cancer and prostate cancer. Additionally, PTP1B acts as a tumor suppressor in other cancers, such as esophageal cancer and lymphoma. These findings suggest that PTP1B functions as a double-facet molecule in tumors, and the… CONTINUE READING