PTP1B inhibitor promotes endothelial cell motility by activating the DOCK180/Rac1 pathway

Abstract

Promoting endothelial cell (EC) migration is important not only for therapeutic angiogenesis, but also for accelerating re-endothelialization after vessel injury. Several recent studies have shown that inhibition of protein tyrosine phosphatase 1B (PTP1B) may promote EC migration and angiogenesis by enhancing the vascular endothelial growth factor receptor… (More)
DOI: 10.1038/srep24111

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