PTK7: a new biomarker for immunophenotypic characterization of maturing T cells and T cell acute lymphoblastic leukemia.

@article{Jiang2012PTK7AN,
  title={PTK7: a new biomarker for immunophenotypic characterization of maturing T cells and T cell acute lymphoblastic leukemia.},
  author={Guohua Jiang and Min Zhang and Baohong Yue and Mingli Yang and Christopher M. Carter and Samer Al-Quran and Bo Li and Ying Li},
  journal={Leukemia research},
  year={2012},
  volume={36 11},
  pages={1347-53}
}
Protein tyrosine kinase-7 (PTK7) was recently identified as a surface protein expressed on hematopoietic cells. To determine if PTK7 is a useful biomarker in clinical practice for acute leukemia immunophenotyping and detection, we examined the PTK7 expression in human bone marrow and thymic specimens. Our results show that PTK7 expression in normal thymic T… CONTINUE READING