PTHrP Expression in Human MDA-MB-231 Breast Cancer Cells Is Critical for Tumor Growth and Survival and Osteoblast Inhibition

Abstract

This study examined the effects of parathyroid hormone-related protein (PTHrP) derived from human MDA-MB-231 breast cancer cells on the tumor growth and osteoblast inhibition. Results revealed that knocking down PTHrP expression in the breast cancer cells strikingly inhibited the formation of subcutaneous tumors in nude mice. PTHrP knockdown dramatically… (More)
DOI: 10.7150/ijbs.7039

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Cite this paper

@inproceedings{Zheng2013PTHrPEI, title={PTHrP Expression in Human MDA-MB-231 Breast Cancer Cells Is Critical for Tumor Growth and Survival and Osteoblast Inhibition}, author={Lu Zheng and Ke Zhu and Hongli Jiao and Zhongfang Zhao and Lixiao Zhang and Mo Liu and Weimin Deng and Di Chen and Zhi Yao and Guozhi Xiao}, booktitle={International journal of biological sciences}, year={2013} }