PTEN Insufficiency Increases Breast Cancer Cell Metastasis In Vitro and In Vivo in a Xenograft Zebrafish Model.

@article{Chiang2016PTENII,
  title={PTEN Insufficiency Increases Breast Cancer Cell Metastasis In Vitro and In Vivo in a Xenograft Zebrafish Model.},
  author={Kun-Chun Chiang and S. Y. Hsu and Sheng-Jia Lin and Chun-Nan Yeh and J. S. Pang and Shang-Yu Wang and Jun-Te Hsu and Ta-Sen Yeh and Li-Wei Chen and Sheng-Fong Kuo and Yi-Chuan Cheng and Horng-Heng Juang},
  journal={Anticancer research},
  year={2016},
  volume={36 8},
  pages={3997-4005}
}
BACKGROUND/AIM Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) insufficiency is commonly found in breast cancer patients with metastasis. We investigated the mechanisms by which PTEN affects breast cancer metastatic behavior. MATERIALS AND METHODS Migration and invasion assay, western blot, immunofluorescent staining and zebrafish animal… CONTINUE READING