PTEN / pAkt / p 53 signaling pathway correlates with the radioresponse of non-small cell lung cancer

@inproceedings{Jung2010PTENP,
  title={PTEN / pAkt / p 53 signaling pathway correlates with the radioresponse of non-small cell lung cancer},
  author={Il Lae Jung and Hyo Jin Kang and Kug Chan Kim and In-Gyu Kim},
  year={2010}
}
The sensitivity or resistance of cancer cells and normal tissues to ionizing radiation plays an important role in the clinical setting of lung cancer treatment. However, to date the exact molecular mechanisms of intrinsic radiosensitivity have not been well explained. In this study, we compared the radiosensitivity or radioresistance in two non-small cell lung cancers (NSCLCs), H460 and A549, and investigated the signaling pathways that confer radioresistance. H460 cells showed a significant G2… CONTINUE READING

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References

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Showing 1-10 of 47 references

EGFR-targeted anti-cancer drugs in radiotherapy: preclinical evaluation of mechanisms.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology • 2007

Phosphatidylinositol 3-kinase inhibition by LY294002 radiosensitizes human cervical cancer cell lines.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2006

Preclinical evaluation of molecular-targeted anticancer agents for radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology • 2006

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