PTEN, energy metabolism and tumor suppression.

Abstract

The tumor suppressor ‘phosphatase and tensin homolog deleted on chromosome 10’ (PTEN) is frequently mutated or deleted in many types of tumors. PTEN germline mutations have been found in several familial cancer predisposition syndromes such as Cowden syndrome, Lhermitte–Duclos disease, Bannayan–Riley–Ruvalcaba syndrome and Proteus and Proteus-like syndromes… (More)
DOI: 10.1093/abbs/gms048

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