PSA nadir predicts biochemical and distant failures after external beam radiotherapy for prostate cancer: a multi-institutional analysis.

@article{Ray2006PSANP,
  title={PSA nadir predicts biochemical and distant failures after external beam radiotherapy for prostate cancer: a multi-institutional analysis.},
  author={Michael E. Ray and Howard D. Thames and Larry B. Levy and Eric Mark Horwitz and Patrick A. Kupelian and Alvaro A. Martinez and Jeff Michael Michalski and Thomas Michael Pisansky and William U. Shipley and Michael J Zelefsky and Anthony Laurence Zietman and Deborah Ann Kuban},
  journal={International journal of radiation oncology, biology, physics},
  year={2006},
  volume={64 4},
  pages={1140-50}
}
PURPOSE To determine the significance of prostate-specific antigen (PSA) nadir (nPSA) and the time to nPSA (T(nPSA)) in predicting biochemical or clinical disease-free survival (PSA-DFS) and distant metastasis-free survival (DMFS) in patients treated with definitive external beam radiotherapy (RT) for clinical Stage T1b-T2 prostate cancer. METHODS AND MATERIALS Nine participating institutions submitted data on 4839 patients treated between 1986 and 1995 for Stage T1b-T2cN0-NxM0 prostate… CONTINUE READING

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