PSA-NCAM in mammalian structural plasticity and neurogenesis.


Polysialic acid (PSA) is a linear homopolymer of alpha2-8-N acetylneuraminic acid whose major carrier in vertebrates is the neural cell adhesion molecule (NCAM). PSA serves as a potent negative regulator of cell interactions via its unusual biophysical properties. PSA on NCAM is developmentally regulated thus playing a prominent role in different forms of… (More)


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@article{Bonfanti2006PSANCAMIM, title={PSA-NCAM in mammalian structural plasticity and neurogenesis.}, author={Luca Bonfanti}, journal={Progress in neurobiology}, year={2006}, volume={80 3}, pages={129-64} }