PS-098 Haemodynamic And Metabolic Effects Of A New Paediatric Dobutamine Formulation In Hypoxic Newborn Piglets

@inproceedings{Mielgo2014PS098HA,
  title={PS-098 Haemodynamic And Metabolic Effects Of A New Paediatric Dobutamine Formulation In Hypoxic Newborn Piglets},
  author={Victoria E. Mielgo and Adolf Valls-i-Soler and J. L. Heredia and Carmen Rey-Santano},
  year={2014}
}
Background Using an age-appropriate new dobutamine formulation, the aims of the study were: to validate superior vena cava flow (SVCF) as a marker of cardiac output (CO), and to study drug-related changes in haemodynamics and oxygen metabolism in response to escalating doses of dobutamine in hypoxic neonatal piglets. Methods 2–days-old-piglets were exposed to hypoxia (10–15% oxygen) for 2 h followed by reoxigenation with 21–30% oxygen for 6 h. After 60-min of reoxigenation, 18 piglets were… CONTINUE READING