PROTS: a fragment based protein thermo-stability potential.

@article{Li2012PROTSAF,
  title={PROTS: a fragment based protein thermo-stability potential.},
  author={Yunqi Li and Jian Zhang and David Tai and C. Russell Middaugh and Yang Arthur Zhang and Jianwen Fang},
  journal={Proteins},
  year={2012},
  volume={80 1},
  pages={
          81-92
        }
}
Designing proteins with enhanced thermo-stability has been a main focus of protein engineering because of its theoretical and practical significance. Despite extensive studies in the past years, a general strategy for stabilizing proteins still remains elusive. Thus effective and robust computational algorithms for designing thermo-stable proteins are in critical demand. Here we report PROTS, a sequential and structural four-residue fragment based protein thermo-stability potential. PROTS is… CONTINUE READING

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