Corpus ID: 17654342

PROTECTIVE EFFECT OF GRAPE SEEDS PROANTHOCYANIDINS AGAINST NAPHTHALENE-INDUCED HEPATOTOXICITY IN RATS

@inproceedings{Ahmed2007PROTECTIVEEO,
  title={PROTECTIVE EFFECT OF GRAPE SEEDS PROANTHOCYANIDINS AGAINST NAPHTHALENE-INDUCED HEPATOTOXICITY IN RATS},
  author={A. A. E. Ahmed and A. Fatani},
  year={2007}
}
Oxidative stress with subsequent production of reactive oxygen species has been postulated as one of the mechanisms of naphthalene toxicity. In the present study, the effect of oral administration of the natural antioxidant and free radical scavenger, proanthocyanidins present in grape seeds (GSP, 10 or 50 mg kg -1 , p.o.), has been investigated in rats following the concomitant administration of naphthalene (1 g kg -1 , p.o., 15 days) and measurement of selective parameters indicative of liver… Expand
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