PROSO II--a new method for protein solubility prediction.

Abstract

Many fields of science and industry depend on efficient production of active protein using heterologous expression in Escherichia coli. The solubility of proteins upon expression is dependent on their amino acid sequence. Prediction of solubility from sequence is therefore highly valuable. We present a novel machine-learning-based model called PROSO II… (More)
DOI: 10.1111/j.1742-4658.2012.08603.x

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