PROPYLENEGLYCOL INTOXICATION DUE TO INTRAVENOUS NITROGLYCERIN

@article{Demey1984PROPYLENEGLYCOLID,
  title={PROPYLENEGLYCOL INTOXICATION DUE TO INTRAVENOUS NITROGLYCERIN},
  author={Hendrik E. Demey and Ronny A. Daelemans and Marc E. De Broe and Leo Bossaert},
  journal={The Lancet},
  year={1984},
  volume={323}
}
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32 Citations
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    PG should be in the differential diagnosis of the disorders with high osmolar gap and may not always be associated with l- or d-lactic acidosis.
    Effects of oral administration of a commercial activated charcoal suspension on serum osmolality and lactate concentration in the dog.
    TLDR
    These laboratory measures and the clinical signs of vomiting, lethargy, and increased frequency of drinking might complicate the diagnosis or monitoring of some intoxications in dogs that have previously received AC suspension containing propylene glycol, glycerol, or both as vehicles.
    Hemodynamic effects of SIN-1 in acute left heart failure
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    The absence of noteworthy side effects and tolerance during this prolonged administration indicate that SIN-1 is a potentially useful drug in the management of patients admitted with exacerbation of heart failure.
    NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Ethylene Glycol.
    • Medicine
      NTP CERHR MON
    • 2004
    TLDR
    An evaluation of the potential for ethylene glycol to cause adverse effects on reproduction and development in humans found that, at high exposure levels, there is no evidence of adverse reproductive effects in mice or rats.
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    References

    SHOWING 1-5 OF 5 REFERENCES
    Hyperosmolality in small infants due to propylene glycol.
    TLDR
    The finding that several infants in the nursery were hyperosmolar due to administration of propylene glycol in a multivitamin preparation used in parenteral nutrition raises concern about the relatively large dose of prophene glycol that may be received by very small infants, especially those receiving multiple medications.
    Hyperosmolality in the burn patient: analysis of an osmolal discrepancy.
    In our study of 262 hospitalized flame burn patients, serum hyperosmolality, defined as having at least two reported osmolality values greater than 310 mOsm/kg, was observed in 15 patients (6%). From…
    Propylene glycol intoxication and lactic acidosis.
    Central nervous system toxicity associated with ingestion of propylene glycol.
    Toxicology, metabolism, and biochemistry of 1,2-propanediol.
    • J. Ruddick
    • Chemistry, Medicine
      Toxicology and applied pharmacology
    • 1972
    TLDR
    Metabolic and chronic studies demonstrate that 1,2-propanediol can be used as a substitute for carbohydrate in the diet of rats and young chicks.