PROFtmb: a web server for predicting bacterial transmembrane beta barrel proteins

  title={PROFtmb: a web server for predicting bacterial transmembrane beta barrel proteins},
  author={Henry R. Bigelow and Burkhard Rost},
  journal={Nucleic Acids Research},
  pages={W186 - W188}
PROFtmb predicts transmembrane beta-barrel (TMB) proteins in Gram-negative bacteria. For each query protein, PROFtmb provides both a Z-value indicating that the protein actually contains a membrane barrel, and a four-state per-residue labeling of upward- and downward-facing strands, periplasmic hairpins and extracellular loops. While most users submit individual proteins known to contain TMBs, some groups submit entire proteomes to screen for potential TMBs. Response time is about 4 min for a… CONTINUE READING

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