PRL-8-53: Enhanced learning and subsequent retention in humans as a result of low oral doses of new psychotropic agent

  title={PRL-8-53: Enhanced learning and subsequent retention in humans as a result of low oral doses of new psychotropic agent},
  author={Nikolaus R. Hansl and Beverley T. Mead},
  • N. Hansl, B. Mead
  • Published 11 April 1978
  • Medicine, Psychology
  • Psychopharmacology
The effect of 3-(2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride (PRL-8-53) on learning and on retention of verbal information in human subjects was investigated. Using the serial anticipation method under double-blind conditions it was found that PRL-8-53 causes slight improvement of acquisition. Retention of verbal information was found improved to a statistically significant degree (most P values better than 0.01, some better than 0.001). No significant changes were found… 


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