PRIMARY BILIARY CIRRHOSIS AND CŒLIAC DISEASE An Association?

@article{Logan1978PRIMARYBC,
  title={PRIMARY BILIARY CIRRHOSIS AND C{\OE}LIAC DISEASE An Association?},
  author={RichardF. A. Logan and Anne Ferguson and Niall D. C. Finlayson and Donald G. Weir},
  journal={The Lancet},
  year={1978},
  volume={311},
  pages={230-233}
}
Abstract The association of primary biliary cirrhosis and cœliac disease, not previously reported, was observed in 4 patients. In each case, the two conditions were diagnosed simultaneously, and although symptoms were due to cœliac disease, initial investigation drew attention to the liver condition. All the patients responded to a gluten-free diet and remain well 2 years later. Primary biliary cirrhosis remains asymptomatic in 3 patients, but pruritus has developed in the 4th. The significance… 

Topics from this paper

An association between primary biliary cirrhosis and jejunal villous atrophy resembling celiac disease
TLDR
A 76-year-old female presented with malabsorption and was subsequently shown to have jejunal villous atrophy and was found to have primary biliary cirrhosis, the fifth recorded instance of this association and the first from North America.
On the concurrence of primary biliary cirrhosis and intestinal villous atrophy.
TLDR
Five out of 26 consecutive patients with primary biliary cirrhosis had intestinal villous atrophy, and no improvement of the liver disease was apparent after 6-22 months on a gluten-free diet.
Hepatobiliary and pancreatic disorders in celiac disease.
  • H. Freeman
  • Medicine
    World journal of gastroenterology
  • 2006
TLDR
Celiac disease may be associated with rare hepatic complications, such as hepatic T-cell lymphoma, and pancreatic exocrine function may be impaired in celiac disease and represent a cause of treatment failure.
Celiac Disease and the Liver
TLDR
This chapter reviews the hepatic involvement in CeD, which includes cryptogenic hepatitis, primary sclerosing cholangitis, primary biliary cholangsitis, non-alcoholic fatty liver disease, and cirrhosis.
Association of hepatic vein obstruction and coeliac disease in North African subjects.
TLDR
This study describes three adults with coeliac disease and hepatic vein obstruction, an association which has not been reported so far, and postulated that this is probably not a chance association, although no link between these diseases and the ethnic origin of the subjects could be elucidated.
Ulcerative colitis, primary sclerosing cholangitis and coeliac disease: two cases and review of the literature
TLDR
It is concluded that patients with a combination of ulcerative colitis, sclerosing cholangitis and coeliac disease should undergo annual colonoscopic surveillance and early liver and bowel imaging should be carried out.
Pathogenesis of steatorrhea in primary biliary cirrhosis
To investigate the pathophysiology of steatorrhea in primary biliary cirrhosis, the severity of steatorrhea, small bowel histology and function, cholestasis, exocrine pancreatic secretion and liver
Hepatic abnormalities in coeliac disease: three cases of delayed diagnosis.
Three cases of biopsy-proven coeliac disease are presented. In each case the predominant clinical and laboratory features suggested liver disease, bowel symptoms were a minor part of the presentation
Primary biliary cirrhosis and lichen planus.
TLDR
Preexisting lichen planus should be regarded as a relative contraindication to the use of D-penicillamine in patients with primary biliary cirrhosis.
Primary sclerosing cholangitis and celiac disease. A novel association.
TLDR
The association of primary sclerosing cholangitis and celiac disease was observed in three patients, an association not previously reported, and the relationship between the two diseases remains unknown, although an immunologic connection is suspected.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 11 REFERENCES
Presentation and course of asymptomatic primary biliary cirrhosis.
TLDR
It is concluded that the diagnosis of asymPTomatic primary biliary cirrhosis is compatible with 10 or more asymptomatic years.
Hepatobiliary diseases associated with serum antimitochondrial antibody (AMA).
TLDR
AMA seems to be a marker for idiopathic parenchymal liver disease, primarily in middle-aged women, but in itself gives no further diagnostic information and does not exclude extrahepatic biliary obstruction.
Inheritance of coeliac disease.
  • W. Mccrae
  • Biology, Medicine
    Journal of medical genetics
  • 1969
TLDR
Present experience seems to indicate that if coeliac disease is defined as a malabsorptive disorder associated with villous atrophy of the jejunum and responding to withdrawal of gluten from the diet, it becomes a sufficiently well-defined entity to make study of its aetiology possible.
Gluten enteropathy appearing after gastric surgery.
TLDR
The findings indicate that evaluation of small bowel function should be undertaken prior to gastric surgery in patients with a family or past history of celiac disease, or symptomatology suggestive of an absorptive defect, and emphasizes the importance of adequate evaluation of the small intestine in Patients with steatorrhea following Gastric surgery.
Histocompatibility Antigens in Active Chronic Hepatitis and Primary Biliary Cirrhosis
TLDR
The frequency of antigens HL-A 1 and HL-a 8 in 54 patients with active chronic hepatitis from south-east England was significantly higher than in 89 control subjects from the same region and the frequency in primary biliary cirrhosis was not significantly different from that found in control groups from thesame regions.
Mitochondrial antibody in primary biliary cirrhosis and other diseases.
Abstract Mitochondrial antibody was detected in the serum in 84% of 188 patients with primary biliary cirrhosis, 11% of 77 with chronic active hepatitis, 6% of 33 with cryptogenic cirrhosis, and 0....
The epidemiology of primary biliary cirrhosis: A survey of mortality in England and Wales
TLDR
The greater frequency of deaths in the London area, a rise in mortality from country to urban areas, a fall-off in deaths from primary biliary cirrhosis in old age, and predominance for social class are suggested.
CŒLIAC DISEASE: A CAUSE OF VARIOUS ASSOCIATED DISEASES?
Deposition in other organs of immune complexes originating from the small-intestinal musosa is suggested as a possible reason, in some patients, for the described association between coeliac disease
Progress in Liver Disease
Whether or not the Australia antigen represents a virus remains to be established; nonetheless, identification of this antigen in the serum of hepatitis patients constitutes a fascinating development
Incidence of Coeliac Disease in the West of Ireland
TLDR
During an 11-year period the incidence of coeliac disease presenting in children in the West of Ireland has been found to be 1 in 597, which is much higher than those reported for Britain.
...
1
2
...