• Chemistry
  • Published 2009

PREPARATION, CHARACTERIZATION AND EVALUATION OFHEPATOPROTECTIVE ACTIVITY OF AN INTRAVENOUS LIPOSOMALFORMULATION OF BIS-DEMETHOXY CURCUMIN ANALOGUE (BDMCA)

@inproceedings{Aukunuru2009PREPARATIONCA,
  title={PREPARATION, CHARACTERIZATION AND EVALUATION OFHEPATOPROTECTIVE ACTIVITY OF AN INTRAVENOUS LIPOSOMALFORMULATION OF BIS-DEMETHOXY CURCUMIN ANALOGUE (BDMCA)},
  author={Jithan Aukunuru and Sreekanth Joginapally and Naresh Gaddam and Madhu Burra and Chandrasekhar R. Bonepally and Kandadi Prabhakar},
  year={2009}
}
The aim of study was to prepare small unilamellar vesicles (SUVs) incorporating BDMCA that can injected by intravenous route and further, evaluate hepatoprotective activity of the formulation. SUV liposomes were prepared using thin film hydration followed by sonication method. Soya lecithin was used as lipid and stearyl amine was used as cationic charge inducer. In the preparation of liposomes, process and formulation parameters were standardized. After preparation SUVs were characterized for… CONTINUE READING

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