PRENYLAMINE‐INDUCED CONTRACTURE OF FROG SKELETAL MUSCLE

@article{Kirsten1977PRENYLAMINEINDUCEDCO,
  title={PRENYLAMINE‐INDUCED CONTRACTURE OF FROG SKELETAL MUSCLE},
  author={E. Kirsten and K. Lustig},
  journal={British Journal of Pharmacology},
  year={1977},
  volume={60}
}
1 Experiments were performed to determine the influence of prenylamine on excitation‐contraction coupling in frog sartorius muscle. 2 Prenylamine (0.2‐1.0 mM) produced a biphasic contracture in skeletal muscle characterized by an initial phasic and subsequent tonic contracture. 3 Neither dantrolene nor procaine blocked the prenylamine‐induced contracture. Pretreatment with 100 mM K+ blocked the phasic but not the tonic component of the prenylamine contracture. 4 Prenylamine produced a sustained… Expand
2 Citations
Pharmacology of calcium release from sarcoplasmic reticulum
TLDR
Activators of Ca2+ release are here tentatively classified as activators of a Ca2-induced Ca2 + release channel preferentially localized in SR terminal or as likely activator of other Ca2+. Expand

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