PREDITOP: a program for antigenicity prediction.

  title={PREDITOP: a program for antigenicity prediction.},
  author={J-L. Pellequer and Eric Westhof},
  journal={Journal of molecular graphics},
  volume={11 3},
  pages={204-10, 191-2}
A program (PREDITOP) for predicting the location of antigenic regions (or epitopes) on proteins is described. This program and the associated ones are written in Turbo Pascal and run on IBM-PC compatibles. The program contains 22 normalized scales, corresponding to hydrophilicity, accessibility, flexibility, or secondary structure propensities. New scales are easily implemented. An hydrophobic moment procedure has also been implemented in order to determine amphiphilic helices. The program… CONTINUE READING