author={Anthony P Corfield and R. C. N. Williamson and Michael J. McMahon and M. G. Shearer and Melbourne J. Cooper and A. David Mayer and A. P. Dickson and C. W. Imrie},
  journal={The Lancet},

Assessment of severity in acute pancreatitis: Use of prognostic factors.

Ranson's prognostic factors help in identifying severe pancreatitis but their accuracy may be improved by the use of modern imaging techniques.

Prediction of severity of acute pancreatitis: an alternative approach.

Admission laboratory data of 203 patients suffering from acute pancreatitis were analysed to search for a simpler method of prediction of severity than the traditional multifactor prognostic scoring system and the predictive ability was comparable with the Glasgow multifactor scoring system.

Outcome in Acute Pancreatitis â An Evaluation of Prognostic Efficacy ofClinical Staging versus CT Severity Index

CTSI is the best scoring system in predicting mortality in patients with acute pancreatitis and has maximum specificity and overall accuracy in predicting whether patients will be cured or relapsed.

Prediction of Mortality in Acute Pancreatitis: A Systematic Review of the Published Evidence

Despite the proliferation of scoring systems for grading AP, none are ideal for the prediction of mortality, and with the exception of the APACHE II, the other scores and indexes do not have a high degree of sensitivity, specificity and predictive values.

Early prediction in acute pancreatitis: the contribution of amylase and lipase levels in peritoneal fluid.

Peritoneal dialysis is less predictive and more cumbersome than a computed tomography scan in the early prediction of acute pancreatitis.

Can We Predict Disease Severity in Acute Pancreatitis?

Patients with a high risk of developing severe pancreatitis could be carefully monitored from the outset and CT scanned to assess the extent of pancreatic necrosis with the possibility of surgical intervention, since the procedures are time consuming, expensive and not without risk.

Role of simplified admission criteria for predicting severe complications of gall stone pancreatitis.

Glucose level is the best single admission predictor of severe complications of Gallstone Pancreatitis and is superior to an APACHE II score of 5 or greater, a modified Imrie score of 3 or great, and a biliary Ranson score of3 or greater.

Comparison of Ranson, APACHE II and APACHE III Scoring Systems in Acute Pancreatitis

Ranson criteria proved to be as powerful a prognostic model as the more complicated APACHE II and III scoring systems, but with the disadvantage of a 24-hour delay.



Early prediction of severity of acute pancreatitis using peritoneal lavage.

Diagnostic peritoneal lavage was attempted in 96 out of a consecutive series of 168 attacks of acute pancreatitis, and resulted in relief of pain in many patients, and in one complication, and it is felt that diagnostic lavage especially suited to select patients who may be expected to benefit from therapeutic peritoneAL lavage.

The role of peritoneal lavage in the prediction and treatment of severe acute pancreatitis.

Patients with predicted 'severe' disease were randomised to receive peritoneal lavage for 72 h or no lavage, but no statistically significant benefit has yet been shown from this treatment.

Acute pancreatitis: analysis of factors influencing survival.

A retrospectiva analysis of 519 cases of acute pancreatitis occurring over a 5-year period was undertaken, finding shock, massive colloid requirement, hypocalcemia, renal failure, and respiratory failure requiring endotracheal intubation were complications associated with the poorest prognosis.

Predictability of present outcome and future recurrence in acute pancreatitis.

Although acute pancreatitis is relatively common, factors useful in predicting immediate outcome or likelihood of recurrence have seldom been studied in greater detail. A ten-year experience with 389

Acute pancreatitis: a lethal disease of increasing incidence.

Between 1968 and 1979 650 patients in the Bristol clinical area suffered 737 attacks of acute pancreatitis, with a mortality rate that was not significantly lower than that of the first attack.

Controlled clinical trial of peritoneal lavage for the treatment of severe acute pancreatitis.

It is concluded that the outcome of severe pancreatitis was not greatly, if at all, influenced by the regimen of peritoneal lavage used in this study.

The Timing of Biliary Surgery in Acute Pancreatitis

It is suggested that although early correction of associated biliary disease may be undertaken safely in many patients with “mild” acute pancreatitis, early definitive surgery is hazardous in “severe” pancreatitis and should, if possible, be deferred until pancreatitis has subsided.

Early assessment of severity of acute pancreatitis using peritoneal lavage.

Lavage successfully predicted severe disease in five patients whose condtion had been clinically assessed as mild, and the concentrations of albumin, aspartate aminotransferase (SGOT) and total protein in the return fluid provided good discrimination between severe and mild attacks.

Acute pancreatitis: clinical vs. CT findings.

On follow-up CT, the findings of acute pancreatitis did not always disappear with resolution of the clinical symptoms, especially true of phlegmonous pancreatitis, where the CT findings could persist for months.

A comparative study of methods for the prediction of severity of attacks of acute pancreatitis

Diagnostic peritoneal lavage was carried out in 79 patients with acute pancreatitis, at a mean time of 7 h after admission to hospital, for the prediction of a severe attack by lavage.