PRAME as diagnostic marker and as regulator for cell fate decisions in germ cell cancers

The study by Nettersheim et al (2016a) is a highly interesting work, revealing the potential of PRAME (preferentially expressed antigen of melanoma) for diagnostic discrimination of human type II germ cell cancers. Moreover, the presented data is incorporated into a model placing PRAME into a decisive position for the cell fate choice with regard to… (More)