PRAME Expression in Melanocytic Tumors.

  title={PRAME Expression in Melanocytic Tumors.},
  author={Cecilia Lezcano and Achim A. Jungbluth and Kishwer S. Nehal and Travis J. Hollmann and Klaus J. Busam},
  journal={The American journal of surgical pathology},
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen that was isolated by autologous T cells in a melanoma patient. While frequent PRAME mRNA expression is well documented in cutaneous and ocular melanomas, little is known about PRAME protein expression in melanocytic tumors. In this study we examined the immunohistochemical… CONTINUE READING