PPARgamma-agonist rosiglitazone increases number and migratory activity of cultured endothelial progenitor cells.

@article{Pistrosch2005PPARgammaagonistRI,
  title={PPARgamma-agonist rosiglitazone increases number and migratory activity of cultured endothelial progenitor cells.},
  author={Frank Pistrosch and Kay Herbrig and Uta Oelschlaegel and Susannne Richter and Jens Passauer and S. T. Fischer and Peter Gross},
  journal={Atherosclerosis},
  year={2005},
  volume={183 1},
  pages={163-7}
}
OBJECTIVE Endothelial progenitor cells (EPC) are involved in the process of endothelial maintenance and angiogenesis and might be related to endothelial function. EPC function was shown to be impaired in type 2 diabetic patients. Since endothelial dysfunction of type 2 diabetic patients can be ameliorated by treatment with thiazolidinediones we asked whether this treatment might also influence number and function of EPC. METHODS AND RESULTS We investigated 10 recently diagnosed type 2… CONTINUE READING
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