PPARalpha and dyslipidemia.

  title={PPARalpha and dyslipidemia.},
  author={Caroline Duval and Michael M{\"u}ller and Sander Kersten},
  journal={Biochimica et biophysica acta},
  volume={1771 8},
Dyslipidemia is defined by abnormal levels of plasma lipoproteins. Several different types of dyslipidemia can be distinguished. An important group of drugs used in the treatment of dyslipidemia are the fibrates. Fibrates serve as agonists for the peroxisome proliferator-activated receptor alpha (PPARalpha), a ligand-activated transcription factor that belongs to the superfamily of nuclear hormone receptors. By binding to response elements mostly present in the promoter of target genes… CONTINUE READING
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