PPARG by dietary fat interaction influences bone mass in mice and humans.

Abstract

Adult BMD, an important risk factor for fracture, is the result of genetic and environmental interactions. A quantitative trait locus (QTL) for the phenotype of volumetric BMD (vBMD), named Bmd8, was found on mid-distal chromosome (Chr) 6 in mice. This region is homologous to human Chr 3p25. The B6.C3H-6T (6T) congenic mouse was previously created to study… (More)
DOI: 10.1359/jbmr.080419

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Cite this paper

@article{AckertBicknell2008PPARGBD, title={PPARG by dietary fat interaction influences bone mass in mice and humans.}, author={Cheryl L. Ackert-Bicknell and Serkalem Demissie and Caralina Mar{\'i}n de Evsikova and Yi-Hsiang Hsu and Victoria Demambro and David Karasik and L. Adrienne Cupples and Jos{\'e} M. Ordov{\'a}s and Katherine L Tucker and Kelly Cho and Ernesto Canalis and Beverly J. Paigen and Gary A. Churchill and Jir{\'i} Forejt and Wesley G. Beamer and Serge Livio Ferrari and Mary L Bouxsein and Douglas P. Kiel and Clifford J. Rosen}, journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research}, year={2008}, volume={23 9}, pages={1398-408} }