PPAR-γ in the Cardiovascular System

@article{Duan2008PPARIT,
  title={PPAR-γ in the Cardiovascular System},
  author={Sheng Duan and Christine Y. Ivashchenko and Michael G. Usher and Richard M. Mortensen},
  journal={PPAR Research},
  year={2008},
  volume={2008},
  pages={2289 - 2304}
}
Peroxisome proliferator-activated receptor-gamma (PPAR-gamma), an essential transcriptional mediator of adipogenesis, lipid metabolism, insulin sensitivity, and glucose homeostasis, is increasingly recognized as a key player in inflammatory cells and in cardiovascular diseases (CVD) such as hypertension, cardiac hypertrophy, congestive heart failure, and atherosclerosis. PPAR-gamma agonists, the thiazolidinediones (TZDs), increase insulin sensitivity, lower blood glucose, decrease circulating… CONTINUE READING

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