PPAR-α agonism improves whole body and muscle mitochondrial fat oxidation, but does not alter intracellular fat concentrations in burn trauma children in a randomized controlled trial

@article{Cree2007PPARAI,
  title={PPAR-α agonism improves whole body and muscle mitochondrial fat oxidation, but does not alter intracellular fat concentrations in burn trauma children in a randomized controlled trial},
  author={Melanie G. Cree and Bradley R. Newcomer and David N . Herndon and Ting Qian and Dayoung Sun and B{\'e}atrice Morio and Jennifer J Zwetsloot and Gerald L Dohm and Ricki Y Fram and Ronald P. Mlcak and Asle A Aarsland and Robert R. Wolfe},
  journal={Nutrition & Metabolism},
  year={2007},
  volume={4},
  pages={9 - 9}
}
BACKGROUND Insulin resistance is often associated with increased levels of intracellular triglycerides, diacylglycerol and decreased fat beta-oxidation. It was unknown if this relationship was present in patients with acute insulin resistance induced by trauma. METHODS A double blind placebo controlled trial was conducted in 18 children with severe burn injury. Metabolic studies to assess whole body palmitate oxidation and insulin sensitivity, muscle biopsies for mitochondrial palmitate… CONTINUE READING
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Fenofibrate improves insulin sensitivity and mitochondrial function in children with burn injury

  • MG Cree, T Qian, +6 authors RR Wolfe
  • Ann Surg
  • 2007
Highly Influential
6 Excerpts

The recovery of labelled acetate in severly burned children 7 days after injury

  • RY Fram, MG Cree, +5 authors RR Wolfe
  • Faseb J 2006,
  • 2006
Highly Influential
2 Excerpts

Isotope Tracers in Metabolic Research. 2nd edition

  • R Wolfe, D Chinkes
  • Wiley-Liss;
  • 2005
1 Excerpt

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