PPARγ ligand treatment inhibits cardiac inflammatory mediators induced by infection with different lethality strains of Trypanosoma cruzi.

@article{Penas2013PPARLT,
  title={PPARγ ligand treatment inhibits cardiac inflammatory mediators induced by infection with different lethality strains of Trypanosoma cruzi.},
  author={Federico Nicol{\'a}s Penas and Gerardo Ariel Mirkin and Eugenia Hovsepian and Agata Cevey and Roberto L. Caccuri and Mar{\'i}a Elena Sales and Nora Beatriz Goren},
  journal={Biochimica et biophysica acta},
  year={2013},
  volume={1832 1},
  pages={239-48}
}
Trypanosoma cruzi (T. cruzi), the etiological agent of Chagas' disease, causes cardiac alterations in the host. Although the main clinical manifestations arise during the chronic stage, the mechanisms leading to heart damage develop early during infection. In fact, an intense inflammatory response is observed from acute stage of infection. Recently, peroxisome proliferator-activated receptors (PPARs) have attracted research interest due to their participation in the modulation of inflammation… CONTINUE READING
12 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…