PPARγ-induced upregulation of CD36 enhances hematoma resolution and attenuates long-term neurological deficits after germinal matrix hemorrhage in neonatal rats

@article{Flores2016PPARinducedUO,
  title={PPARγ-induced upregulation of CD36 enhances hematoma resolution and attenuates long-term neurological deficits after germinal matrix hemorrhage in neonatal rats},
  author={Jerry J. Flores and Damon Klebe and William B. Rolland and Tim Lekic and John H Zhang},
  journal={Neurobiology of Disease},
  year={2016},
  volume={87},
  pages={124-133}
}
Germinal matrix hemorrhage remains the leading cause of morbidity and mortality in preterm infants in the United States with little progress made in its clinical management. Survivors are often afflicted with long-term neurological sequelae, including cerebral palsy, mental retardation, hydrocephalus, and psychiatric disorders. Blood clots disrupting normal cerebrospinal fluid circulation and absorption after germinal matrix hemorrhage are thought to be important contributors towards post… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Effects of Posthemorrhagic Ventricular Dilatation in the Preterm Infant on Brain Volumes and White Matter Diffusion Variables at Term-Equivalent Age

  • Brouwer, J M.
  • J Pediatr
  • 2015

Neonatal Research Network

  • Q Z., Z. J. Liu
  • Am J Obstet Gynecol
  • 2015

Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-gamma agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease

  • A Pisanu
  • Neurobiol Dis
  • 2014

Similar Papers

Loading similar papers…