PPARγ co-activator-1α co-activates steroidogenic factor 1 to stimulate the synthesis of luteinizing hormone and aldosterone.

Abstract

The orphan nuclear receptor SF-1 (steroidogenic factor 1) is highly expressed in the pituitary, gonad and adrenal glands and plays key roles at all levels of the hypothalamic-pituitary-steroidogenic tissue axis. In the present study, we show that PGC-1α [PPARγ (peroxisome-proliferator-activated receptor γ) co-activator 1α] interacts with and co-activates SF… (More)
DOI: 10.1042/BJ20100460

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Cite this paper

@article{Zhu2010PPARCC, title={PPARγ co-activator-1α co-activates steroidogenic factor 1 to stimulate the synthesis of luteinizing hormone and aldosterone.}, author={Liuluan Zhu and Yaojun Ke and Di Shao and Ying Cui and Aijun Qiao and Xiaojun Michael Liu and Fude Fang and Yongsheng Chang}, journal={The Biochemical journal}, year={2010}, volume={432 3}, pages={473-83} }