PPARγ and Apoptosis in Cancer

@article{Elrod2008PPARAA,
  title={PPARγ and Apoptosis in Cancer},
  author={Heath A. Elrod and Shi-yong R Sun},
  journal={PPAR Research},
  year={2008},
  volume={2008},
  pages={237 - 244}
}
Peroxisome proliferator-activated receptors (PPARs) are ligand binding transcription factors which function in many physiological roles including lipid metabolism, cell growth, differentiation, and apoptosis. PPARs and their ligands have been shown to play a role in cancer. In particular, PPARgamma ligands including endogenous prostaglandins and the synthetic thiazolidinediones (TZDs) can induce apoptosis of cancer cells with antitumor activity. Thus, PPARgamma ligands have a potential in both… CONTINUE READING

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References

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Inhibitors of the arachidonic acid pathway and peroxisome proliferator-activated receptor ligands have superadditive effects on lung cancer growth inhibition

I. Avis, A. Martı́nez, J. Tauler
Cancer Research, vol. 65, no. 10, pp. 4181– 4190, 2005. • 2005
View 9 Excerpts
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