POTENTIATION OF AN EFFECT OF ALLOPURINOL ON PYRIMIDINE METABOLISM BY CHLOROTHIAZIDE IN MAN

@article{Wood1974POTENTIATIONOA,
  title={POTENTIATION OF AN EFFECT OF ALLOPURINOL ON PYRIMIDINE METABOLISM BY CHLOROTHIAZIDE IN MAN},
  author={M. H. Wood and W. O'Sullivan and M. Wilson and D. Tiller},
  journal={Clinical and Experimental Pharmacology and Physiology},
  year={1974},
  volume={1}
}
SUMMARY 1. Treatment with allopurinol leads to increased excretion of the pyrimidine compounds orotic acid and orotidine, and to increased levels in erythrocytes of the enzymes orotate phosphoribosyltransferase and orotidylate decarboxylase. 
Clinical Pharmacokinetics of Allopurinol
Interaction of allopurinol and hydrochlorothiazide during prolonged oral administration of both drugs in normal subjects
Effect of increasing low-dose simplexin exposure in cattle consuming Pimelea trichostachya.
Hyperuricemia and gout.

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