• Corpus ID: 212582600

POTENTIAL BENEFIT OF CURCUMIN ADJUVANT THERAPY TO THE STANDARD HELICOBACTER PYLORI ERADICATION THERAPY IN PATIENTS WITH PEPTIC ULCER DISEASE

@inproceedings{Abbas2017POTENTIALBO,
  title={POTENTIAL BENEFIT OF CURCUMIN ADJUVANT THERAPY TO THE STANDARD HELICOBACTER PYLORI ERADICATION THERAPY IN PATIENTS WITH PEPTIC ULCER DISEASE},
  author={Shaymaa Hasan Abbas and Manal Khalid Abdulridha and Akram Ajeel Najeb},
  year={2017}
}
Objective: This study was designed to explore the benefit of curcumin as adjuvant therapy to the standard Helicobacter pylori eradication triple therapy in both duodenal and gastric ulcers patients. Methods: The present study enrolled 40 patients newly diagnosed endoscopically with peptic ulcer disease to be allocated into group 1 treated with standard H. pylori eradication triple therapy, and group 2 patients treated with curcumin (500 mg) capsules three times daily for 14 days as an adjuvant… 
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References

SHOWING 1-10 OF 64 REFERENCES

Investigation of the anti-inflammatory effect of Curcuma longa in Helicobacter pylori-infected patients.

Curcumin Inhibits Gastric Inflammation Induced by Helicobacter Pylori Infection in a Mouse Model

Curcumin treatment exerted a significant anti-inflammatory effect in H. pylori-infected mucosa, pointing to the promising role of a nutritional approach in the prevention of H.pylori induced deleterious inflammation while the eradication or prevention of colonization by effective vaccine is not available.

Comparative Evaluation of the Anti-ulcer Activity of Curcumin and Omeprazole during the Acute Phase of Gastric Ulcer—Efficacy of Curcumin in Gastric Ulcer Prevention against Omeprazole

Curcumin and omeprazole are potentially preventing gastric lesions development in the gastric wall during the acute phase of gastric ulcer diseases, but curcumin was more potent in its effect.

Meta-analysis: Duration of First-Line Proton-Pump InhibitorBased Triple Therapy for Helicobacter pylori Eradication

An updated meta-analysis of RCTs comparing the efficacy of different durations of triple therapy is performed to verify whether current recommendations reflect the available data and to determine the optimum duration for PPI-based triple therapy for H. pylori eradication.

Antimicrobial Activity of Curcumin against Helicobacter pylori Isolates from India and during Infections in Mice

Novel insights are provided into the therapeutic effect of curcumin against H. pylori infection, suggesting its potential as an alternative therapy, and opens the way for further studies on identification of novel antimicrobial targets ofCurcumin.

Helicobacter pylori therapy: Present and future.

This work reviewed both bacterial and host factors involved in therapeutic management of the H. pylori infection and evaluated data on the most successful therapy regimens - sequential and concomitant therapies - currently available for H.pylori eradication.

Curcumin Alleviates Matrix Metalloproteinase-3 and -9 Activities during Eradication of Helicobacter pylori Infection in Cultured Cells and Mice

Data indicate that curcumin-mediated healing of Hp-infection involves regulation of MMP-3 and -9 activities.

Risk factors and therapeutic response in Chinese patients with peptic ulcer disease.

Patients with gastric ulcers had lower H. pylori infection but more aspirin or NSAID use than those with duodenal ulcers, while tobacco smoking and alcohol drinking had no different impact between these two groups.

Predicting Helicobacter pylori eradication: how to teach an old dog new tricks!

Although Helicobacter pylori prevalence is markedly decreased in the last decades, a large endoscopic survey recently found that such an infection is still present in 15% to 20% of US patients, and to identify predictors of therapeutic success would seem to be clinically relevant.

RESPONSE TO FIRST- LINE QUADRUPLE AND SECOND-LINE QUADRUPLE H PYLORI ERADICATION THERAPY IN IRAQI PATIENTS WITH PEPTIC ULCER DISEASE

According to the data obtained from Iraqi population, secondline H. pylori eradication quadruple therapy is as effective as firstline quadruple Therapy that can be used as a rescue therapy after failure of triple H. Pylori regimen.
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