POPSIM: a general population simulation program

@article{Hampe1998POPSIMAG,
  title={POPSIM: a general population simulation program},
  author={Jochen Hampe and T. Wienker and Stefan Schreiber and P. Nurnberg},
  journal={Bioinformatics},
  year={1998},
  volume={14 5},
  pages={458-64}
}
MOTIVATION The investigation of common disorders of polygenic inheritance using both population-based association designs and non-parametric linkage analysis within families is gaining increasing importance. We have created a program that allows for the flexible simulation of populations as a tool to investigate the properties of population-based mapping approaches. RESULTS We have created a population simulation program, POPSIM, that (i) creates a virtual representation of every individual… CONTINUE READING

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