POLYAR, a new computer program for prediction of poly(A) sites in human sequences

@inproceedings{Akhtar2010POLYARAN,
  title={POLYAR, a new computer program for prediction of poly(A) sites in human sequences},
  author={Malik N. Akhtar and Syed Abbas Bukhari and Zeeshan Fazal and Raheel Qamar and Ilham A. Shahmuradov},
  booktitle={BMC Genomics},
  year={2010}
}
mRNA polyadenylation is an essential step of pre-mRNA processing in eukaryotes. Accurate prediction of the pre-mRNA 3'-end cleavage/polyadenylation sites is important for defining the gene boundaries and understanding gene expression mechanisms. 28761 human mapped poly(A) sites have been classified into three classes containing different known forms of polyadenylation signal (PAS) or none of them (PAS-strong, PAS-weak and PAS-less, respectively) and a new computer program POLYAR for the… CONTINUE READING