POEMS syndrome: 2014 update on diagnosis, risk-stratification, and management.

@article{Dispenzieri2014POEMSS2,
  title={POEMS syndrome: 2014 update on diagnosis, risk-stratification, and management.},
  author={Angela Dispenzieri},
  journal={American journal of hematology},
  year={2014},
  volume={89 2},
  pages={
          214-23
        }
}
DISEASE OVERVIEW POEMS syndrome is a paraneoplastic syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyradiculoneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease. Minor features include organomegaly, endocrinopathy, characteristic skin changes, papilledema, extravascular volume overload, and thrombocytosis. Diagnoses are often delayed because the… CONTINUE READING

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