PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis.

@article{Guyot2013PNPLA3RH,
  title={PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis.},
  author={Erwan Guyot and A Sutton and Pierre Rufat and Christelle Laguillier and Abdellah Mansouri and Richard Moreau and Nathalie Ganne-Carri{\'e} and Michel Beaugrand and Nathalie Charnaux and J C Trinchet and Pierre Nahon},
  journal={Journal of hepatology},
  year={2013},
  volume={58 2},
  pages={312-8}
}
BACKGROUND & AIMS Several studies have reported an association between the genetic variant rs738409 (G) in the PNPLA3 gene and the risk of cirrhosis in various liver diseases. Our purpose was to assess the influence of this polymorphism on the risk of hepatocellular carcinoma (HCC) occurrence in two distinct longitudinal cohorts of patients with cirrhosis as well as its possible usefulness in HCC-risk model prediction. METHODS PNPLA3 rs738409 genotypes were assessed in 279 patients with… CONTINUE READING

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Impact of patatinlike phospholipase3 ( rs 738409 C > G ) polymorphism on fibrosis progression and steatosis in chronic hepatitis C

  • E Trepo, P Pradat, A Potthoff, Y Momozawa, E Quertinmont, T Gustot
  • Hepatology
  • 2011

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