PKHD1 post‐transcriptionally modulated by miR‐365‐1 inhibits cell‐cell adhesion

@article{Duan2012PKHD1PM,
  title={PKHD1 post‐transcriptionally modulated by miR‐365‐1 inhibits cell‐cell adhesion},
  author={J. Duan and H. Huang and Xiaoyan Lv and Honglian Wang and Ziwei Tang and Huan Sun and Qingwei Li and Jianzhong Ai and Ruizhi Tan and Yuhang Liu and Mianzhi Chen and Weiwei Duan and Yuquan Wei and Qin Zhou},
  journal={Cell Biochemistry and Function},
  year={2012},
  volume={30}
}
Autosomal recessive polycystic kidney disease (ARPKD) is a severe inherited disorder with an incidence of 1/20 000 live births. Mutations of PKHD1 (polycystic kidney and hepatic disease gene 1) gene were identified to be responsible for ARPKD. However, the underlying molecular mechanisms remain largely unknown. MicroRNAs (miRNAs) are an abundant class of small RNAs with global effect on gene expression. Up to 30% of human protein coding genes may be regulated by miRNAs. However, to date… Expand
Non-Coding RNAs in Hereditary Kidney Disorders
  • Julie Xia Zhou, Xiaogang Li
  • Medicine
  • International journal of molecular sciences
  • 2021
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