PKC activation is required by EGF-stimulated Na+-H+ exchanger in human pleural mesothelial cells.

@article{Liaw1998PKCAI,
  title={PKC activation is required by EGF-stimulated Na+-H+ exchanger in human pleural mesothelial cells.},
  author={Y Liaw and Pan-Chyr Yang and Chong-Jen Yu and S H Kuo and K. T. Luh and Yuh-Jeng Lin and M L Wu},
  journal={The American journal of physiology},
  year={1998},
  volume={274 5 Pt 1},
  pages={L665-72}
}
Epidermal growth factor (EGF) stimulates the Na+-H+exchanger, leading to enhanced cell proliferation. In human pleural mesothelial cells (PMCs), the intracellular signaling mechanism mediating the EGF-induced stimulation of the Na+-H+exchanger has not yet been identified. Using a pH-sensitive fluorescent probe, 2',7'-bis(2-carboxyethyl)-5(6… CONTINUE READING