PKCλ/ι regulates Th17 differentiation and house dust mite-induced allergic airway inflammation.

Abstract

Asthma is a chronic airway inflammation in which Th2 and Th17 cells play critical roles in its pathogenesis. We have reported that atypical protein kinase (PKC) λ/ι is a new regulator for Th2 differentiation and function. However, the role of PKCλ/ι for Th17 cells remains elusive. In this study, we explored the effect of PKCλ/ι on Th17 cells in the context… (More)
DOI: 10.1016/j.bbadis.2018.01.001

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