PKCα promotes the mesenchymal to amoeboid transition and increases cancer cell invasiveness

@inproceedings{Vakoviov2015PKCPT,
  title={PKCα promotes the mesenchymal to amoeboid transition and increases cancer cell invasiveness},
  author={Katar{\'i}na Va{\vs}kovi{\vc}ov{\'a} and Emilia Szabadosov{\'a} and Vladimir Cermak and Aneta Gandalovi{\vc}ov{\'a} and Lenka Kasalov{\'a} and Daniel R{\"o}sel and Jan Br{\'a}bek},
  booktitle={BMC Cancer},
  year={2015}
}
The local invasion of tumor cells into the surrounding tissue is the first and most critical step of the metastatic cascade. Cells can invade either collectively, or individually. Individual cancer cell invasion can occur in the mesenchymal or amoeboid mode, which are mutually interchangeable. This plasticity of individual cancer cell invasiveness may… CONTINUE READING