PII is important in regulation of nitrogen metabolism but not required for heterocyst formation in the Cyanobacterium Anabaena sp. PCC 7120.

@article{Zhang2007PIIII,
  title={PII is important in regulation of nitrogen metabolism but not required for heterocyst formation in the Cyanobacterium Anabaena sp. PCC 7120.},
  author={Ying Zhang and Hai Pu and Qingsong Wang and Shu Pei Cheng and Weixing Zhao and Yan Zhang and Jindong Zhao},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 46},
  pages={33641-8}
}
PII is an important signal protein for regulation of nitrogen metabolism in bacteria and plants. We constructed a mutant of glnB, encoding PII, in a heterocystous cyanobacterium, Anabaena sp. PCC 7120, with a cre-loxP system. The mutant (MP2alpha) grew more slowly than the wild type under all nitrogen regimens. It excreted a large amount of ammonium when grown on nitrate due to altered activities of glutamine synthetase and nitrate reductase. MP2alpha had a low nitrogenase activity but was able… CONTINUE READING